Osteopontin Exacerbates High-Fat Diet-Induced Metabolic Disorders in a Microbiome-Dependent Manner
ABSTRACT The gut microbiome is involved in metabolic disorders.Osteopontin (OPN), as a key cytokine, contributes to various inflammation-related diseases.The underlying role of OPN in the microbiome remains poorly understood.Here, we investigated whether OPN could modulate metabolic disorders by affecting gut microbiota.In our present study, we fou